why is aldactone a hazardous drug

ByMaksim L.

Sep 14, 2022

Why do you have to wear gloves with spironolactone?

Wear gloves when handling Spironolactone tablets. Prolonged exposure to Spironolactone can cause birth defects, reproductive harm, cancer, or organ damage.

What is the main adverse effect of spironolactone?

This medication may lead to high levels of potassium, especially in patients with kidney problems. If not treated, very high potassium levels can be fatal. Tell your doctor right away if you notice any of the following serious side effects: slow/irregular heartbeat, muscle weakness.

Is spironolactone a high risk medication?

Spironolactone is widely used to treat heart failure, hypertension and liver disease with increased usage in recent years. Spironolactone has endocrine effects that could influence cancer risks and historical reports suggest possible links with increased risk of certain types of cancer.

What should be monitored when taking Aldactone?

The recommended monitoring for potassium and creatinine is one week after initiation or increase in dose of Aldactone, monthly for the first 3 months, then quarterly for a year, and then every 6 months. Discontinue or interrupt treatment for serum potassium > 5 mEq/L or for serum creatinine > 4 mg/dL.

What foods should you avoid when taking spironolactone?

Since spironolactone is a potassium-sparing diuretic, you should avoid taking potassium in your supplements or sports drinks and avoid eating too many high potassium foods such as papaya, cantaloupe, prune juice, honeydew melons, bananas, raisins, mangoes, kiwis, oranges, orange juice, tomatoes, tomato juice, white and …

Does spironolactone have a black box warning?

There is a black box warning for spironolactone stating that it may increase certain tumors, which has been shown in animal studies, but Dr. Graber notes that the dosage of medication was significantly higher than what is prescribed for women to treat acne.

Can spironolactone damage your kidneys?

Diuretics, or water pills, are used to treat conditions like high blood pressure, glaucoma, and edema, but as with all medications, they come with some risks. Popular diuretics include hydrochlorothiazide, furosemide, and spironolactone. They are associated with a risk for acute kidney injury.

What happens if you eat too much potassium while taking spironolactone?

If any of the signs or symptoms of high blood potassium are experienced while taking spironolactone, get immediate medical attention. These symptoms can include muscle weakness, fatigue, nausea, vomiting, tingling, trouble breathing, heart palpitations, irregular heartbeats, and chest pain.

Can spironolactone cause Steven Johnson Syndrome?

They may be able to recommend a treatment to help ease your discomfort. Although unlikely, you may experience a severe skin reaction while taking Aldactone. These reactions include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

Does spironolactone cause Tumours?

Spironolactone has caused tumors in animals. These studies used larger than normal doses for a long time. Use this drug as you have been told. Do not use this drug for health problems other than what the doctor told you.

Is spironolactone safe for long term use?

There are sufficient data to suggest that long-term use of spironolactone appears to be safe overall. This was revealed in one long-term study with patients who received spirono-lactone for up to eight years for the treatment of AV.

What class of drugs is spironolactone?

Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

When should you not take Aldactone?

  1. a condition where the adrenal glands produce less hormones called Addison’s disease.
  2. low amount of sodium in the blood.
  3. high levels of potassium in the blood.
  4. acute kidney failure.
  5. decreased kidney function.
  6. decreased blood volume.
  7. cessation of urine production.
  8. hyperchloremic acidosis.

What happens when you stop spironolactone?

You shouldn’t stop taking spironolactone without first talking with your doctor. Stopping this medication suddenly won’t cause withdrawal symptoms. But when you stop taking spironolactone it will quickly stop working to manage your condition.

Should I drink a lot of water with spironolactone?

Be sure to drink adequate water while taking spironolactone. Watch for signs of dehydration, including: excessive thirst. infrequent urination.

Why does spironolactone make you gain weight?

For example, if you take spironolactone for heart failure or edema (fluid retention and swelling) you’re likely to lose weight as your body gets rid of excess fluid. On the other hand, if spironolactone isn’t working well to treat these conditions, your body may retain more fluid. And this can lead to weight gain.

Can you drink while taking spironolactone for acne?

Spironolactone is used to treat conditions such as liver disease, where alcohol should be avoided. If you’re taking spironolactone for these conditions, do not drink alcohol.

What happens if you stop taking spironolactone for acne?

“If you discontinue spironolactone, the skin slowly will return back to what it’s genetically programmed to do,” he explains. “Acne typically returns within a few months [after stopping the drug].”

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